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The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform
JoVE Journal
Genetics
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JoVE Journal Genetics
The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform
DOI:

10:01 min

September 27, 2016

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Chapters

  • 00:05Title
  • 01:05Detecting Multi-nucleotide Polymorphisms by Hybridization-mediated Growth of Gold Nanoparticles
  • 03:36Fabrication of the Pneumatic Droplet Manipulation Platform
  • 05:58Detecting Multi-nucleotide Polymorphisms on the Pneumatic Droplet Manipulation Platform
  • 07:21Results: Colorimetric Detection of Multi-nucleotide Polymorphisms
  • 08:24Conclusion

Summary

Automatic Translation

This work presents a simple and visual method to detect multi-nucleotide polymorphisms on a pneumatic droplet manipulation platform. With the proposed method, the entire experiment, including droplet manipulation and detection of multi-nucleotide polymorphisms, can be performed near 23 °C without the aid of advanced instruments.

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