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Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair
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Developmental Biology
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JoVE Journal Developmental Biology
Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair

Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair

DOI:
10.3791/55142-v

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06:37 min

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February 03, 2017

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, ,
1Department of Biomedical Engineering, School of Medicine, School of Engineering,University of Alabama at Birmingham

Chapters

  • 00:05Title
  • 01:05Differentiating Human-induced Pluripotent Stem Cells into Cardiomyocytes
  • 02:41Patch-mediated Cell Transplantation in a Swine Model of Ischemia-reperfusion Injury
  • 04:08Results: Characterizing Cardiomyocytes and Treatment Results
  • 05:38Conclusion

Summary

Automatic Translation

Automatic Translation

We present three novel and more efficient protocols for differentiating human induced pluripotent stem cells into cardiomyocytes, endothelial cells, and smooth muscle cells and a delivery method that improves the engraftment of transplanted cells by combining cell injection with patch-mediated cytokine delivery.

Tags

Pluripotent Stem CellsCardiomyocytesMyocardial RepairIschemia Reperfusion InjuryIPS CellsCardiac CellsSmooth Muscle CellsEndothelial CellsMyocardial InfarctionCoronary Artery OcclusionFibrinogenMicrospheres

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