05:46Covalent Coupling Technique of BMP2-K3Plk to Azide Functionalized Agarose Beads
07:04Measuring Alkaline Phosphatase (ALP) Expression to Prove the In Vitro Bioactivity of the Produced BMP2-K3Plk Before and After the Coupling Reaction
08:34Results: Evaluation of the Bioactivity of BMP2-K3Plk after Site-Directed Immobilization
Biomaterials doped with Bone Morphogenetic Protein 2 (BMP2) have been used as a new therapeutic strategy to heal non-union bone fractures. To overcome side effects resulting from an uncontrollable release of the factor, we propose a new strategy to site-directly immobilize the factor, thus creating materials with improved osteogenic capabilities.