Journal
/
/
Acellular and Cellular Lung Model to Study Tumor Metastasis
JoVE Journal
Cancer Research
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Cancer Research
Acellular and Cellular Lung Model to Study Tumor Metastasis
DOI:

08:31 min

August 19, 2018

,

Chapters

  • 00:04Title
  • 00:48Rat Lung Harvest
  • 02:16Lung Decellularization
  • 03:28Bioreactor Setup
  • 05:43Metastasis Model and Cell Seeding
  • 07:05Results: Representative Images of the Ex Vivo 4-D Lung Model for Metastasis
  • 08:02Conclusion

Summary

Automatic Translation

Here, we present a protocol for an ex vivo lung cancer model that mimics the steps of tumor progression and helps to isolate a primary tumor, circulating tumor cells, and metastatic lesions.

Related Videos

Read Article