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JoVE Journal Neuroscience
Misurazione quantitativa delle proteine intratecalliamente sintetizzate nei topi
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Misurazione quantitativa delle proteine intratecalliamente sintetizzate nei topi

Article DOI: 10.3791/60495-v • 08:23 min • November 29th, 2019
November 29th, 2019 •
1, 1,2, 1,2, 1, 1, 1
1Department of Neurology, Geisel School of Medicine & Dartmouth-Hitchcock Medical Center, 2Program in Experimental and Molecular Medicine, Dartmouth College

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Livelli elevati di proteine del fluido spinale possono essere il risultato della diffusione della proteina plasmatica attraverso una barriera emato-encefalica alterata o sintesi intratea. In questo articolo viene presentato un protocollo di test ottimizzato che aiuta a discriminare entrambi i casi e fornisce misurazioni quantitative delle proteine sintetizzate intrathecally.

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Neuroscienze numero 153 sintesi intratecale liquido cerebrospinale barriera emato-encefalica quozienti di albumina indice proteico transudate proteico
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