JoVE Journal

Cancer Research

JoVE Cancer Research includes experimental approaches and methods to understand, detect, treat, and prevent cancer.

1 2 3 4 5 6 7 8 9…13 › 305 VIDEO ARTICLES

A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties

Carlemi Calitz¹, Nataša Pavlović¹, Jenny Rosenquist², Claudia Zagami¹, Ayan Samanta², Femke Heindryckx¹

¹Department of Medical Cell Biology, Uppsala University, ²Polymer Chemistry, Department of Chemistry-Ångström Laboratory, Uppsala University

JoVE 61606

Methods Collection

Assays for Validating Histone Acetyltransferase Inhibitors

Aaron R. Waddell¹, Daiqing Liao¹

¹Department of Anatomy and Cell Biology, and UF Health Cancer Center, University of Florida College of Medicine

JoVE 61289

Perfusion and Inflation of the Mouse Lung for Tumor Histology

Mackenzie L. Davenport¹, Taylor P. Sherrill², Timothy S. Blackwell², Mick D. Edmonds¹

¹Department of Genetics, University of Alabama at Birmingham, ²Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine

JoVE 60605

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Piyan Zhang¹, Irina V. Kovtun^1,2

¹Center for Individualized Medicine, Mayo Clinic, ²Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic

JoVE 60646

Management of Respiratory Motion Artefacts in ¹⁸F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Willem Grootjans¹, Peter Kok², Jurrian Butter², Erik Aarntzen²

¹Department of Radiology, Leiden University Medical Centre, ²Department of Radiology and Nuclear Medicine, Radboud University Medical Centre

JoVE 60258

Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres

Chun-Chia Cheng¹, Po-Jui Hsu⁴, Zong-Lin Sie¹, Fang-Hsin Chen^1,2,3

¹Radiation Biology Research Center, Institute for Radiological Research, Chang Gung University, Chang Gung Memorial Hospital at Linkou, ²Department of Medical Imaging and Radiological Sciences, Chang Gung University, ³Department of Radiation Oncology, Chang Gung Memorial Hospital, ⁴Department of Laboratory Medicine, Mackay Memorial Hospital

JoVE 61077

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors

Lester J. Lambert¹, Celeste Romero¹, Douglas J. Sheffler¹, Maria Celeridad¹, Nicholas D. P. Cosford¹, Lutz Tautz¹

¹Cancer Metabolism & Signaling Networks Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute

JoVE 61457

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis

Iftekhar A. Showpnil^1,2, Kyle R. Miller¹, Cenny Taslim¹, Kathleen I. Pishas¹, Stephen L. Lessnick^1,3, Emily R. Theisen^1,4

¹Center for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, ²Molecular, Cellular, and Developmental Biology Program, The Ohio State University, ³Division of Pediatric Hematology/Oncology/Blood & Marrow Transplant, The Ohio State University, ⁴Department of Pediatrics, The Ohio State University

JoVE 61564

Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture

Yuan-Na Lin¹, Apsra Nasir¹, Sharon Camacho¹, Deborah L. Berry¹, Marcel O. Schmidt¹, Gray W. Pearson¹, Anna T. Riegel¹, Anton Wellstein¹

¹Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University

JoVE 61392

Methods Collection

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells

Jina Lee*^1,2, Joo-Eun Lee*³, Seil Kim^1,4,5, Dukjin Kang¹, Hee Min Yoo¹

¹Microbiological Analysis Team, Group for Biometrology, Korea Research Institute of Standards and Science (KRISS), ²College of Pharmacy, Chungnam National University (CNU), ³Stem Cell Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), ⁴Convergent Research Center for Emerging Virus Infection, Korea Research Institute of Chemical Technology (KRICT), ⁵Department of Bio-Analysis Science, University of Science & Technology (UST)

JoVE 61285

Immunofluorescence Imaging of DNA Damage and Repair Foci in Human Colon Cancer Cells

Kamila Maliszewska-Olejniczak¹, Agnieszka Dróżdż¹, Martyna Waluś¹, Michał Dorosz¹, Michał A. Gryziński¹

¹Nuclear Facilities Operations Department, National Centre for Nuclear Research, Sołtana 7, 05-400 Otwock, Poland

JoVE 61399

Methods Collection

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Claudia Rengucci¹, Giulia De Maio¹, Maura Menghi², Francesca Benzi², Daniele Calistri¹

¹Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), ²Diatech Pharmacogenetics srl

JoVE 59426

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Jennifer A. Geisler^1,2,3, Jonathan M. Spehar^1,2, Sarah A. Steck^1,2, Anna Bratasz^1,4, Reena Shakya¹, Kimerly Powell^1,4, Gina M. Sizemore^1,2

¹The Comprehensive Cancer Center, The Ohio State University, ²Department of Radiation Oncology, The Ohio State University, ³Department of Veterinary Biosciences, The Ohio State University, ⁴Davis Heart & Lung Research Institute, The Ohio State University

JoVE 61272

Methods Collection

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Katie A Thies¹, Sue E Knoblaugh², Steven T Sizemore¹

¹Department of Radiation Oncology, Arthur G. James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, ²Department of Veterinary Biosciences, Comparative Pathology and Digital Imaging Shared Resource, The Ohio State University

JoVE 61270

Methods Collection

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer

Xiangdong Lv*^1,2,3, Lacey E. Dobrolecki*^1,2,3, Yao Ding^1,2,3, Jeffrey M. Rosen^1,2,3, Michael T. Lewis^1,2,3, Xi Chen^1,2,3

¹Department of Molecular and Cellular Biology, Baylor College of Medicine, ²Lester and Sue Smith Breast Center, Baylor College of Medicine, ³Dan L. Duncan Cancer Center, Baylor College of Medicine

JoVE 61173

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

Gururaj Shivange*^1,2, Tanmoy Mondal*^1,2, Evan Lyerly^1,2, Jeremy Gatesman³, Jogender Tushir-Singh^1,2

¹Laboratory of Novel Biologics, University of Virginia School of Medicine, ²Department of Biochemistry and Molecular Genetics, UVA Cancer Center, University of Virginia School of Medicine, ³Center for Comparative Medicine, University of Virginia

JoVE 60727

An Automated Differential Nuclear Staining Assay for Accurate Determination of Mitocan Cytotoxicity

Jingqi Pei*¹, Svetlana B. Panina*¹, Natalia V. Kirienko¹

¹Department of BioSciences, Rice University

JoVE 61295

Combined Conditional Knockdown and Adapted Sphere Formation Assay to Study a Stemness-Associated Gene of Patient-derived Gastric Cancer Stem Cells

Jixian Xiong*¹, Yuting Li*¹, Xiangyu Tan*¹, Li Fu¹

¹Guangdong Key Laboratory of Genome Stability and Human Disease Prevention, Department of Pharmacology and Shenzhen University International Cancer Center, Shenzhen University School of Medicine

JoVE 60799

In Vivo Targeting of Xenografted Human Cancer Cells with Functionalized Fluorescent Silica Nanoparticles in Zebrafish

Xiaodan Qin*¹, Fabrice F. J. Laroche*¹, Saquib Ahmed M. A. Peerzade², Andrew Lam¹, Igor Sokolov^2,3,4, Hui Feng¹

¹Departments of Pharmacology and Medicine, Section of Hematology and Medical Oncology, The Cancer Research Center, Boston University School of Medicine, ²Department of Biomedical Engineering, Tufts University, ³Department of Mechanical Engineering, Tufts University, ⁴Department of Physics, Tufts University

JoVE 61187

Measuring Real-time Drug Response in Organotypic Tumor Tissue Slices

Nao Nishida-Aoki¹, Andrew J. Bondesson^1,2, Taranjit S. Gujral^1,2,3

¹Division of Human Biology, Fred Hutchinson Cancer Research Center, ²Department of Molecular and Cellular Biology, University of Washington, ³Department of Pharmacology, University of Washington

JoVE 61036

Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells

Yuri Frosi, Siti Radhiah Ramlan, Christopher J. Brown

¹p53 Laboratory, Neuros/Immunos, A*STAR (Agency for Science, Technology and Research)

JoVE 60850

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

Neal K. Ramchandani¹, Kenneth A. Kesler¹, Jonathon D. Rogers¹, Nakul Valsangkar¹, Samatha M. Stokes¹, Shadia I. Jalal²

¹Department of Surgery, Division of Cardiothoracic, Indiana University Melvin and Bren Simon Cancer Center, ²Department of Medicine, Medical Oncology Division, Indiana University Melvin and Bren Simon Cancer Center

JoVE 59255

Drug Screening of Primary Patient Derived Tumor Xenografts in Zebrafish

Meghan G. Haney^1,2, L. Henry Moore¹, Jessica S. Blackburn^1,2

¹Department of Molecular and Cellular Biochemistry, University of Kentucky, ²Markey Cancer Center, University of Kentucky

JoVE 60996

A 3D Spheroid Model for Glioblastoma

Joris Guyon^1,2, Laetitia Andrique^1,2, Nadège Pujol^1,2, Gro Vatne Røsland^3,4, Gaelle Recher^1,5,6, Andreas Bikfalvi^1,2, Thomas Daubon^1,2,4

¹University Bordeaux, LAMC, ²INSERM U1029, University Bordeaux, ³Department of Biomedicine, University of Bergen, ⁴CNRS, IBGC UMR5095, ⁵LP2N, CNRS UMR 5298, IOA, ⁶Institut d'Optique Graduate School, IOA

JoVE 60998

1 2 3 4 5 6 7 8 9…13 ›

RELATED SECTIONS

Biochemistry

Biology

Genetics

Medicine

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Your free access has ended.