Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Author Produced

This content is Open Access.

Engineering Cell-permeable Protein

Engineering Cell-permeable Protein

Article DOI: 10.3791/1627-v 21:09 min December 28th, 2009
December 28th, 2009



Protein transduction enables the direct delivery of biologically active proteins into cells. In contrast to conventional methods such as DNA transfection or viral transduction this non-invasive paradigm allows highly efficient cellular manipulation in a titratable manner circumventing cellular toxicity and the risk of oncogenic transformation by permanent genetic modification.


Protein Transduction Cell-permeable Protein Cell Penetrating Peptides Protein Transduction Domains TAT-CPP Nuclear Localization Signal Engineering DNA-modifying Enzyme Cre Site-specific Recombinase LoxP Sites PSESAME Vector System
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter