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免疫相关动态三级的HIV - 1 V3环冠R2的序列结构特点的评估从头折叠
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
DOI:

10:50 min

September 15, 2010

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Chapters

  • 00:00Title
  • 01:07Introduction
  • 01:57R2 HIV-1 Strain V3 Loop ab initio Folding via the ICM-Pro GUI
  • 04:19R2 HIV-1 Strain V3 Loop ab initio Folding via the ICM-Pro Command Line
  • 06:35 ab initio Folding Data Analysis
  • 08:41Representative Results for R2 HIV-1 Strain V3 Loop ab initio Folding
  • 09:59Conclusion

Summary

Automatic Translation

冠表面的HIV - 1包膜糖蛋白(gp120的)不同的V3的循环序列区域的结构特点,在许多情况下,在硅片的立场折叠10日至22日对一个国家的最先进的循环使用<em>从头</em>折叠算法。在这里,我们展示了这一地区从R2的HIV - 1菌株,一个独特的令人费解的功能特性的敏感株中和与V3环的折叠和评价。

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