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JoVE Journal
Biology

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Silicon Microchips for Manipulating Cell-cell Interaction
 

Silicon Microchips for Manipulating Cell-cell Interaction

Article doi: 10.3791/268
August 30th, 2007

Summary August 30th, 2007

This article describes an experimental approach for dynamic regulation of cell-cell interactions between adherent cells on a micrometer scale. Manipulation of intercellular communication between hepatocytes and stromal cell is demonstrated. The developed platform enables investigation of cell-cell interactions in a variety of biological processes, including development and pathogenesis.

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