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JoVE Journal
Biology

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Silicon Microchips for Manipulating Cell-cell Interaction
 
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Silicon Microchips for Manipulating Cell-cell Interaction

Article doi: 10.3791/268
August 30th, 2007

Summary August 30th, 2007

Please note that all translations are automatically generated.

Click here for the English version.

This article describes an experimental approach for dynamic regulation of cell-cell interactions between adherent cells on a micrometer scale. Manipulation of intercellular communication between hepatocytes and stromal cell is demonstrated. The developed platform enables investigation of cell-cell interactions in a variety of biological processes, including development and pathogenesis.

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