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幸免神经损伤(SNI)模型引起的机械触感小鼠
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
The Spared Nerve Injury (SNI) Model of Induced Mechanical Allodynia in Mice
Please note that all translations are automatically generated.
Click here for the English version.
幸免神经损伤(SNI)模型引起的机械触感小鼠
DOI:
10.3791/3092-v
•
07:44 min
•
August 18, 2011
•
Mette Richner
,
Ole J. Bjerrum
,
Anders Nykjaer
,
Christian B. Vaegter
1
The Lundbeck Foundation Research Center MIND, Department of Biomedicine
,
Aarhus University
,
2
Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences
,
University of Copenhagen
Chapters
00:05
Title
01:56
Collecting Baseline von Frey Measurements Prior to Surgery
03:04
Anesthesia and Preparation for Surgery
04:14
Surgery
06:04
Post-surgical Care and von Frey Measurements
06:37
Results: von Frey Testing of 8-10 Week-old Mice Before and After Surgery
07:17
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
幸免神经损伤的动物模型是描述以下的坐骨神经损毁的胫骨和腓总神经分支部分失神经支配的周围神经痛的小鼠模型,保持其余的腓肠神经不变。行为矫正机械触感量化冯弗雷细丝。
Tags
Spared Nerve Injury (SNI) Model
Peripheral Neuropathic Pain
Chronic Pain Condition
Trauma To Sensory Nerves
Peripheral Nervous System
Mechanical Allodynia
Tactile Stimuli
SNI Mouse Model
Ligation Of Sciatic Nerve Branches
Tibial Nerve
Common Peroneal Nerve
Sural Nerve
Hypersensitivity In Lateral Area Of Paw
Control Side
Von Frey Filaments
Bending Force
Pain Reaction
Paw Withdrawal
Flinching
Paw Licking
Pain Threshold
Article
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