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Induktion af graft-versus-host sygdom og<em> In Vivo</em> T Cell Monitoring Brug en MHC-matchet murin model
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Chapters
- 00:05Title
- 01:10Lethal Irradiation and Splenocyte Preparation
- 03:12Bone Marrow Preparation and Removal
- 05:16CD3 Depletion
- 06:08L2G85.B6 (LUX+) CD8+ T Cell Purification and Injection Preparation
- 07:48Bioluminescent Imaging
- 08:12Results
- 10:12Conclusion
Murin knoglemarvstransplantation er en meget anvendt teknik til at undersøge immunologiske mekanismer for transplantat-versus-host-sygdom hos mennesker. Muligheden for at overvåge T-celle trafficking mønstre<em> In vivo</em> Giver mulighed for detaljeret analyse af udviklingen og bevarelsen af T-celle responser under graft-versus-host sygdom.
