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Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count
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Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count

Article DOI: 10.3791/3969-v • 13:06 min • July 11th, 2012
July 11th, 2012 •
1, 1, 1
1Department of Biomedical Engineering, McGill University, Montreal, QC Canada

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Nanoparticles such as semiconductor quantum dots (QDs) can be used to create photoactivatable agents for anti-microbial or anti-cancer applications. This technique shows how to water-solubilize cadmium telluride (CdTe) QDs, conjugate them to an antibiotic, and perform a bacterial inhibition assay based upon growth curves and plate count.

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Quantum Dots Solubilization Bio-conjugation Bacterial Toxicity Assays Growth Curve Plate Count Fluorescence Imaging Diagnostics Therapy Cytotoxic Agents Targeted Killing Of Bacteria Multiply-resistant Bacterial Strains Public Health Crisis Gram Negative Pathogens Nanomaterials Antimicrobial Effect Toxicity Of Nanoparticles To Bacteria Semiconductor Nanoparticles TiO2 ZnO CuO Oxidation Reactive Oxygen Species (ROS) Metal Ions
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