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En<em> In vitro</em> Samtidig infektion model for at studere<em> Plasmodium falciparum</em>-HIV-1 Interactions i humane primære Monocytafledte immunceller
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Chapters
- 00:05Title
- 01:45Plasmodium falciparum-infected Red Blood Cell (iRBC) Purification
- 02:35Exposure of Monocyte-derived Macrophages (MDM) to Plasmodium falciparum
- 03:40Infection of MDM with a Fully Replicative HIV-1
- 04:44Infection of MDM with Single Cycle Virus Encoding Luciferase
- 05:56Results: Exposure of P. falciparum to MDM Decreases their Susceptibility to HIV-1 Infection
- 07:16Conclusion
Vi har udviklet en<em> In vitro</em> Malaria-HIV-1 co-infektion model for at undersøge virkningen af<em> Plasmodium falciparum</em> På HIV-1 replikativ cyklus i humane primære monocyt-afledte makrofager. Dette alsidige system kan let tilpasses andre primære celletyper modtagelige for HIV-1 infektion.
Tags
In Vitro Co-infection ModelPlasmodium FalciparumHIV-1 InteractionsHuman Primary Monocyte-derived Immune CellsMalariaHIV-1Co-infectionsDisease ProgressionTransmissionImmunological MechanismsSoluble Malarial AntigensHIV-1 InfectionReactivationImmune CellsP. Falciparum Schizont Stage ParasitesPeripheral Blood Mononuclear Cells
