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Un<em> In vitro</em> Co-infezione da modello per lo studio<em> Plasmodium falciparum</em>-HIV-1 in Interazioni umane Le cellule immunitarie primarie derivate da monociti
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Chapters
- 00:05Title
- 01:45Plasmodium falciparum-infected Red Blood Cell (iRBC) Purification
- 02:35Exposure of Monocyte-derived Macrophages (MDM) to Plasmodium falciparum
- 03:40Infection of MDM with a Fully Replicative HIV-1
- 04:44Infection of MDM with Single Cycle Virus Encoding Luciferase
- 05:56Results: Exposure of P. falciparum to MDM Decreases their Susceptibility to HIV-1 Infection
- 07:16Conclusion
Abbiamo sviluppato uno<em> In vitro</em> Malaria-HIV-1 co-infezione da modello per studiare l'impatto di<em> Plasmodium falciparum</em> Sul ciclo replicativo di HIV-1 in primarie umane derivate da monociti macrofagi. Questo sistema versatile può essere facilmente adattato ad altri tipi di cellule primarie sensibili a HIV-1.
Tags
In Vitro Co-infection ModelPlasmodium FalciparumHIV-1 InteractionsHuman Primary Monocyte-derived Immune CellsMalariaHIV-1Co-infectionsDisease ProgressionTransmissionImmunological MechanismsSoluble Malarial AntigensHIV-1 InfectionReactivationImmune CellsP. Falciparum Schizont Stage ParasitesPeripheral Blood Mononuclear Cells
