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甲状腺未分化癌的原位小鼠模型
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Please note that all translations are automatically generated.
Click here for the English version.
甲状腺未分化癌的原位小鼠模型
DOI:
10.3791/50097-v
•
07:01 min
•
April 17, 2013
•
Will Sewell
,
Ashley Reeb
,
Reigh-Yi Lin
1
Department of Internal Medicine, Division of Endocrinology
,
Saint Louis University School of Medicine
Chapters
00:05
Title
01:14
Cell Preparation
02:43
Surgery Preparation
03:54
Surgical Access to Thyroid and Cell Injection
04:44
Post-operative Care and Tissue Collection
05:30
Results: Histological Verification of Anaplastic Thyroid Carcinoma
06:35
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
这里描述的甲状腺未分化癌的原位小鼠模型生成。这种技术采用的人甲状腺未分化癌的细胞免疫缺陷小鼠进入甲状腺手术放置,从而创造了更多的临床相关的设置,研究疾病的进展,以及屏幕创新的治疗干预。
Tags
Orthotopic Mouse Model
Anaplastic Thyroid Carcinoma
Subcutaneous Xenograft
Thyroid Cancer
Tumor Microenvironment
Metastasis
Preclinical Screening
Therapeutic Evaluation
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