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斑马鱼模型的糖尿病和代谢记忆
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JoVE Journal Medicine
A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
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斑马鱼模型的糖尿病和代谢记忆

DOI:
10.3791/50232-v

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10:03 min

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February 28, 2013

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, ,
1Dr. William M. Scholl College of Podiatric Medicine,Rosalind Franklin University of Medicine and Science, 2Chicago Medical School,Rosalind Franklin University of Medicine and Science

Chapters

  • 00:05Title
  • 01:51Generation of Zebrafish with Diabetes Mellitus
  • 04:26Blood Collection and Fasting Blood Glucose Level (FBGL) Determination
  • 05:51Caudil Fin Regeneration
  • 07:17Generation of Metabolic Memory Zebrafish
  • 08:46Representative Fin Regeneration Results
  • 09:38Conclusion

Summary

Automatic Translation

Automatic Translation

代谢记忆的现象，其中糖尿病并发症的坚持和畅通，即使血糖正常，取得药学进展。在这里，我们描述了一个糖尿病斑马鱼模型的独特之处在于它允许参加考试的有丝分裂传播后生成分代谢记忆<em在体内</em>。

Tags

ZebrafishDiabetes MellitusMetabolic MemoryEpigeneticsDiabetic ComplicationsRegenerationWound HealingCaudal Fin

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