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A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
 

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Article DOI: 10.3791/50232
February 28th, 2013

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Summary February 28th, 2013

Metabolic memory is the phenomenon by which diabetic complications persist and progress unimpeded even after euglycemia is achieved pharmaceutically. Here we describe a diabetes mellitus zebrafish model which is unique in that it allows for the examination of the mitotically transmissible epigenetic components of metabolic memory in vivo.

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