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JoVE Journal
Biology

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Rapid Generation of Amyloid from Native Proteins In vitro
 

Rapid Generation of Amyloid from Native Proteins In vitro

Article DOI: 10.3791/50869 05:48 min
December 5th, 2013

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Summary December 5th, 2013

Proteins can either adopt a native structure or misfold into insoluble amyloid. Conditions that favor the misfolding pathway lead to the formation of different types of amyloid fibrils. The methods described here allow rapid conversion of native proteins into amyloid in vitro.

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