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Den ChroP Approach Kombinerar Chip och masspektrometri att dissekera Locus-specifika Proteomic Landscapes of Chromatin
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Den ChroP Approach Kombinerar Chip och masspektrometri att dissekera Locus-specifika Proteomic Landscapes of Chromatin

Article DOI: 10.3791/51220-v • 24:02 min • April 11th, 2014
April 11th, 2014 •
1, 1
1Department of Experimental Oncology, European Institute of Oncology

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Genom att kombinera infödda och tvärbindning kromatin immunoprecipitation med högupplösande masspektrometri, ChroP metod gör det möjligt att dissekera den sammansatta proteomik arkitektur histon modifikationer, varianter och icke-histonic proteiner synergizing på funktionellt distinkta kromatin domäner.

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Biokemi kromatin histon post-translationella modifieringar (hPTMs) epigenetik masspektrometri proteomik SILAC kromatin immunoprecipitation histon varianter chromatome hPTMs kors samtalen
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