A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Christine J. Fontaine; Bandhan Mukherjee; Gillian L. Morrison; Qi Yuan

doi:10.3791/51808

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Een gelateraliseerde Geur Learning Model in pasgeboren ratten voor Prepareernaald Neural Circuits Underpinning Memory Formation

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Een gelateraliseerde Geur Learning Model in pasgeboren ratten voor Prepareernaald Neural Circuits Underpinning Memory Formation

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8,883 Views

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10:42 min

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August 18, 2014

DOI:

10.3791/51808-v

DOI:

10.3791/51808-v

•

10:42 min

August 18, 2014

•

4 Views

Christine J. Fontaine*^1,2, Bandhan Mukherjee*¹, Gillian L. Morrison¹, Qi Yuan¹

¹Division of Biomedical Sciences,Faculty of Medicine, Memorial University, ²Division of Medical Sciences,University of Victoria

Summary

This protocol introduces lateralized early odor preference learning in rats using acute single naris occlusion. Lateralized learning permits the examination of behavioral outcomes and underpinning biological mechanisms within the same animals, reducing variance induced by between-animal designs. This protocol can be used to investigate molecular mechanisms underpinning early odor learning.