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通过鼻腔活检获得联合激光捕获显微切割的嗅觉神经元:一种可能的方法来研究治疗反应的精神障碍
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
DOI:

08:33 min

December 04, 2014

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Chapters

  • 00:05Title
  • 01:49Laser-Capture Microdissection
  • 03:48Isolation of Total RNA and cDNA Synthesis
  • 05:50Real Time PCR Quantification
  • 07:14Reults: GSK-3β Expression in OE Neurons
  • 07:53Conclusion

Summary

Automatic Translation

在这项研究中,一种新的平台来调查在躁郁症(BD)的治疗的反应的突触体分子签名被开发和验证。从BD患者嗅上皮是通过鼻腔活检获得。那么激光捕获显微切割是结合实时RT PCR,调查BD锂反应的分子签名。

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