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大脑侧向颅骨切开术大脑活动的中尺度广角光学成像
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Neuroscience
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JoVE Journal Neuroscience
A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity
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大脑侧向颅骨切开术大脑活动的中尺度广角光学成像

DOI:
10.3791/52642-v

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10:05 min

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May 07, 2017

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, , , ,
1Canadian Center for Behavioural Neuroscience,University of Lethbridge

Chapters

  • 00:05Title
  • 01:01Surgery Preparation
  • 02:28Removing the Skin and Retracting the Muscle from the Skull
  • 04:35Craniotomy
  • 06:36Dura Removal and Cranial Window Preparation
  • 08:15Results: Unique and Consensus Activation Patterns during Multiple Forms of Sensory Stimulation
  • 09:04Conclusion

Summary

Automatic Translation

Automatic Translation

该协议提出了在小鼠大脑皮质的时间和顶叶区域产生大单方面开颅的方法。这对于实时成像在皮质半球的一个广阔的区域是特别有用的。

Tags

Large Lateral CraniotomyMesoscale Wide-field Optical ImagingBrain ActivityNeural DynamicsBrain Circuit DevelopmentOptogeneticsAlzheimer’s DiseaseStrokeAnesthetized MouseThermo-regulating Heating PadDexamethasoneLidocaineDissecting MicroscopeTemporal Muscle

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