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JoVE Journal
Immunology and Infection

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Selective Harvesting of Marginating-hepatic Leukocytes

Selective Harvesting of Marginating-hepatic Leukocytes

Article DOI: 10.3791/53918
July 21st, 2016


Summary July 21st, 2016

Marginating-hepatic leukocytes exhibit unique characteristics and distinct immunological functions compared to other leukocyte populations. Here we describe a method for selective harvesting of this specific hepatic cell population, through forced perfusion of the liver of rats or mice. Marginating-hepatic leukocytes seem critical in determining susceptibility to hepatic-related diseases and metastases.


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