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Micropatterning and Assembly of 3D Microvessels
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Bioengineering
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JoVE Journal Bioengineering
Micropatterning and Assembly of 3D Microvessels

Micropatterning and Assembly of 3D Microvessels

DOI:
10.3791/54457-v

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13:05 min

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September 09, 2016

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, , ,
1Department of Bioengineering,University of Washington, 2Center for Cardiovascular Biology, Institute for Stem Cell and Regenerative Medicine,University of Washington

Chapters

  • 00:05Title
  • 00:58Micro-vessel Device Assembly: Part 1
  • 05:19Micro-vessel Device Assembly: Part 2
  • 07:39Cell Seeding and Culturing
  • 10:46Results: Experimental Applications
  • 12:14Conclusion

Summary

Automatic Translation

Automatic Translation

This manuscript presents an injection molding method to engineer microvessels that recapitulate physiological properties of endothelium. The microfluidic-based process creates patent 3D vascular networks with tailorable conditions, such as flow, cellular composition, geometry, and biochemical gradients. The fabrication process and examples of potential applications are described.

Tags

Keywords: Micropatterning3D MicrovesselsVascular PhysiologyVascular BiologyVessel FabricationPDMS MoldsPMMA HousingPlasma TreatmentPEIGlutaraldehydeCollagenVessel Assembly

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