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JoVE Journal Genetics
Optogenetic caso Mutagenesi Utilizzando istone-miniSOG in
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Optogenetic caso Mutagenesi Utilizzando istone-miniSOG in

Article DOI: 10.3791/54810
November 14th, 2016 •
1, 1,2
1Division of Biological Sciences, Section of Neurobiology, University of California in San Diego and Howard Hughes Medical Institute, 2Department of Cellular and Molecular Medicine, University of California in San Diego School of Medicine and Howard Hughes Medical Institute

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November 14th, 2016

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Geneticamente codificato istone-miniSOG induce genome-wide mutazioni ereditarie in un modo dipendente dalla luce blu. Questo metodo mutagenesi è semplice, veloce, privo di sostanze chimiche tossiche, e ben si adatta per lo screening genetico in avanti e l'integrazione del transgene.

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