3D Whole-heart Myocardial Tissue Analysis

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Medicine

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Medicine

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JoVE Journal Medicine

3D Whole-heart Myocardial Tissue Analysis

DOI:

10.3791/54974-v

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06:53 min

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April 12, 2017

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Hans Thijs Van den Broek, Leon De Jong², Pieter A. Doevendans, Steven A.J. Chamuleau, Frebus J. Van Slochteren*¹, René Van Es*¹

¹Department of Cardiology, Division Heart and Lungs,University Medical Center Utrecht, ²MIRA Institute,University Twente

Chapters

00:05Title
01:01Embedding Procedure
03:01Tissue Processing and Fluorescence Imaging
04:57Results: Representative Ex Vivo Imaging and 3D Reconstruction
06:02Conclusion

Summary

Automatic Translation

This protocol describes a novel method for the 3D comparison of whole-heart myocardial tissue with MRI. This is designed for the accurate assessment of intramyocardial injections in the infarct border zone of a chronic porcine model of myocardial infarction.

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