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Journal / Genetics / Der Nachweis von Copy Number Änderungen Single…
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Genetics

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JoVE Journal Genetics
Der Nachweis von Copy Number Änderungen Single Cell-Sequenzierung
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Der Nachweis von Copy Number Änderungen Single Cell-Sequenzierung

Article DOI: 10.3791/55143-v • 09:45 min • February 17th, 2017
February 17th, 2017 •
1,2,3, 4, 5
1Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, 2Howard Hughes Medical Institute, 3Division of Health Sciences and Technology, Harvard Medical School, 4The Barbara K. Ostrom (1978) Bioinformatics and Computing Facility in the Swanson Biotechnology Center, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 5BioMicro Center, Department of Biology, Massachusetts Institute of Technology

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Einzelne Zell Sequenzierung ist ein immer beliebter und zugängliches Werkzeug für genomische Veränderungen bei hoher Auflösung Adressierung. Wir bieten ein Protokoll, das einzelne Zelle Sequenzierung verwendet Kopienzahl Veränderungen in einzelnen Zellen zu identifizieren.

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Genetik Ausgabe 120 Kopienzahl Veränderung Aneuploidie genomische Heterogenität einzelne Zelle Amplifikation des gesamten Genoms Sequenzierung ganzer Genome
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