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Cancer Research
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人地幔细胞淋巴瘤移植小鼠模型中肿瘤植入的研究
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Cancer Research
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Please note that all translations are automatically generated.
Click here for the English version.
人地幔细胞淋巴瘤移植小鼠模型中肿瘤植入的研究
DOI:
10.3791/56023-v
•
10:52 min
•
March 30, 2018
•
Archana Vijaya Kumar
2
,
Carmen Donate
,
Beat A. Imhof
,
Thomas Matthes
1
Department of Pathology and Immunology
,
University of Geneva
,
2
Hematology Service
,
University Hospital, Geneva
Chapters
00:05
Title
01:23
Preparation of Primary Peripheral Blood Mononuclear Cells by Density Gradient Separation
03:15
Enrichment of B Cells Negative Selection
05:34
Development of the Xenograft Mouse Model
06:07
Chimerism Analysis of Tumor Cell Engrafted in Different Organs
07:43
Results: Use of Flow Cytometry to Analyze the B Cell Enrichment in Mice Xenografts Obtained from Mantle Cell Lymphoma Patients
09:08
Conclusion
Summary
Automatic Translation
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Automatic Translation
地幔细胞淋巴瘤 (MCL) 是一种难以治疗 B 细胞紊乱的方法, 建立一只移植小鼠模型 MCL 的研究和开发治疗同样困难。在这里, 我们描述成功地建立了 MCL 移植在小鼠, 以帮助了解其基础生物学。
Tags
Xenograft Mouse Model
Mantle Cell Lymphoma
Hematooncology
Therapeutic Outcome
Patient-derived Xenografts
B Cell Migration
Density Gradient Media
Mononuclear Blood Cells
Phosphate Buffered Saline
Cell Suspension
Cell Pellet
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