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反复臭氧暴露对小鼠慢性阻塞性肺疾病模型的产生
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Medicine
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JoVE Journal
Medicine
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Please note that all translations are automatically generated.
Click here for the English version.
反复臭氧暴露对小鼠慢性阻塞性肺疾病模型的产生
DOI:
10.3791/56095-v
•
08:17 min
•
August 25, 2017
•
Zhongwei Sun
2
,
Feng Li
,
Xin Zhou
,
Wen Wang
2
1
Cellular Biomedicine Group, Shanghai
,
2
Cellular Biomedicine Group, Cupertino
,
3
Department of Respiratory Medicine, Shanghai General Hospital
,
Shanghai Jiaotong University
Chapters
00:05
Title
00:52
Ozone Air Exposure and Treadmill Test
02:17
Pulmonary Function Measurements
03:05
Broncheoalveolar Lavage Fluid (BALF) Collection
04:25
Cardiac Blood Sampling and Lung Morphometric Analysis
06:06
Results: Representative Chronic Obstructive Pulmonary Disease Mouse Model
07:29
Conclusion
Summary
Automatic Translation
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Automatic Translation
这项研究描述了一个新的慢性阻塞性肺疾病 (COPD) 动物模型的成功生成, 反复暴露小鼠到高浓度的臭氧。
Tags
COPD Model
Ozone Exposure
Mice
Lung Function
Micro-CT Imaging
Treadmill Test
Bronchoalveolar Lavage
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