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Journal / Neuroscience / 利用瞬态受体电位辣椒1型 Ultrapotent…
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Neuroscience

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JoVE Journal Neuroscience
利用瞬态受体电位辣椒1型 Ultrapotent 激动剂建立单纯小纤维神经病变的小鼠模型
Removal of Drosophila Muscle Tissue from Larval Fillets for Immunofluorescence Analysis of Sensory Neurons and Epidermal Cells
Journal (Neuroscience)
Removal of Drosophila Muscle Tissue from Larval Fillets for Immunofluorescence Analysis of Sensory Neurons and Epidermal Cells
A Method for High Fidelity Optogenetic Control of Individual Pyramidal Neurons In vivo
Journal (Neuroscience)
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利用瞬态受体电位辣椒1型 Ultrapotent 激动剂建立单纯小纤维神经病变的小鼠模型

Article DOI: 10.3791/56651 • 09:39 min
February 13th, 2018 •
1,2, 3, 1,2
1Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University, 2Department of Medical Research, Kaohsiung Medical University Hospital, 3Department of Medical Research, Ultrastructural Laboratory, Kaohsiung Medical University Hospital

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February 13th, 2018

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本研究建立了树酯毒素 (RTX) 纯小纤维神经病变的实验模型。独特剂量的 RTX (50 µg/千克) 是最佳的发展一个小纤维神经病变模型, 模仿病人的特点, 并可以帮助调查的伤害性分子意义下的神经病理性疼痛。

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