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Journal / Neuroscience / 基于细胞荧光检测平台的γ-分泌介导的淀粉样前体蛋白和缺口裂解的定量测定…
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Neuroscience

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JoVE Journal Neuroscience
基于细胞荧光检测平台的γ-分泌介导的淀粉样前体蛋白和缺口裂解的定量测定
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基于细胞荧光检测平台的γ-分泌介导的淀粉样前体蛋白和缺口裂解的定量测定

Article DOI: 10.3791/56795-v • 06:40 min • January 25th, 2018
January 25th, 2018 •
*1, *1, *1, 1, 1, 1, 1
1Laboratory of Molecular Neurobiology, Institute of Cellular and Organismic Biology, Academia Sinica
* These authors contributed equally

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我们已经成功地生成了两个基片特定的γ-分泌检测。这两种基于细胞的检测方法都被设计成通过萤火虫荧光记者的输出来量化γ-分泌酶的活性。

Tags

神经科学 问题 131 淀粉样前体蛋白 缺口 γ-分泌 萤火虫荧光 ErbB2 阿尔茨海默病 淀粉样β
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