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Journal / Bioengineering / Overflate Functionalization av hepatitt E Virus…
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JoVE Journal Bioengineering
Overflate Functionalization av hepatitt E Virus nanopartikler bruke kjemiske Bøyning
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Overflate Functionalization av hepatitt E Virus nanopartikler bruke kjemiske Bøyning

Article DOI: 10.3791/57020-v • 09:12 min • May 11th, 2018
May 11th, 2018 •
*1, *1, 1, 1
1Department of Molecular and Cellular Biology, University of California Davis
* These authors contributed equally

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Vi har konstruert kapsid protein av hepatitt E som en theranostic hydrogenion (HEVNP). HEVNP samler selv i en stabil icosahedral bur mucosal levering. Her beskriver vi endring av HEVNPs for svulst målretting etter mutere overflaten-eksponerte rester til cysteinene, hvilke bøy syntetiske ligander som spesifikt binder kreftceller.

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Bioteknologi problemet 135 cystein erstatning kjemiske Bøyning hepatitt E virus-lignende partikler multivalent ligand display målretting ligand
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