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Genetics
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通过重叠
2
方法高通量识别协同药物组合
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High-throughput Identification of Synergistic Drug Combinations by the Overlap
2
Method
Please note that all translations are automatically generated.
Click here for the English version.
通过重叠
2
方法高通量识别协同药物组合
DOI:
10.3791/57241-v
•
07:51 min
•
May 21, 2018
•
Morgan A. Wambaugh
,
Jessica C. S. Brown
1
Microbiology and Immunology Division, Department of Pathology
,
University of Utah
Chapters
00:04
Title
00:49
Identifying Synergy Prediction Mutants from Chemical-genetics Dataset by the Overlap2 Method
01:17
Validation of Predicted Synergistic Interactions
04:52
High-throughput Screen with Synergy Prediction Mutants to Identify the Novel Synergistic Pairs
05:21
Results: Use of Checkerboard Assay to Identify and Validate Synergistic Drug Molecules
07:05
Conclusion
Summary
Automatic Translation
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Automatic Translation
协同药物组合是困难和耗时的鉴定经验。在这里, 我们描述了一种识别和验证协同小分子的方法。
Tags
Synergistic Drug Combinations
High-throughput Screening
Antimicrobial Drugs
Infectious Diseases
E. Coli
M9 Minimal Medium
Small Molecules
Optical Density
Checkerboard Assay
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