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重複2法による相乗効果の薬剤の組合せの高スループット識別
JoVE Journal
Genetics
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JoVE Journal Genetics
High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
DOI:

07:51 min

May 21, 2018

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Chapters

  • 00:04Title
  • 00:49Identifying Synergy Prediction Mutants from Chemical-genetics Dataset by the Overlap2 Method
  • 01:17Validation of Predicted Synergistic Interactions
  • 04:52High-throughput Screen with Synergy Prediction Mutants to Identify the Novel Synergistic Pairs
  • 05:21Results: Use of Checkerboard Assay to Identify and Validate Synergistic Drug Molecules
  • 07:05Conclusion

Summary

Automatic Translation

相乗効果の薬剤の組み合わせは難しいと経験的に識別するために時間がかかるです。ここでは、識別し相乗小分子を検証する手法について述べる。

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