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雄激素依赖性和去势抗性前列腺癌的荧光自体小鼠模型
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal
Cancer Research
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Please note that all translations are automatically generated.
Click here for the English version.
雄激素依赖性和去势抗性前列腺癌的荧光自体小鼠模型
DOI:
10.3791/57301-v
•
07:25 min
•
March 06, 2018
•
Jonathan F. Anker
,
Hanlin Mok
,
Anum F. Naseem
,
Praveen Thumbikat*
1,3
,
Sarki A. Abdulkadir*
1,2,3
1
Department of Urology
,
Northwestern University Feinberg School of Medicine
,
2
The Robert H. Lurie Comprehensive Cancer Center
,
Northwestern University Feinberg School of Medicine
,
3
Department of Pathology
,
Northwestern University Feinberg School of Medicine
Chapters
00:05
Title
00:59
Intra-prostatic Injection
04:37
Results: Representative Orthotopic Murine Prostate Tumor Analyses
06:17
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
本协议的目的是证明前列腺癌细胞内注射, 随后阉割。在临床相关的肿瘤微环境和免疫宿主的背景下, 应用雄激素依赖性和抗去势前列腺癌的原位前模型是研究该病的关键。
Tags
Bioluminescent
Fluorescent
Orthotopic
Syngeneic
Murine
Prostate Cancer
Androgen-dependent
Castration-resistant
Intra-prostatic Injection
Tumor Microenvironment
Genetic Modification
Orthotopic Tumor
Therapy
Mouse
Seminal Vesicle
Anterior Prostate Lobe
Matrigel
Cancer Cell Solution
28-gauge Needle
Article
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