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1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center,Ohio State University Wexner Medical Center, 2Department of Surgery, Division of Transplant,Ohio State University Wexner Medical Center, 3Department of Surgery, Division of CardioThoracic Surgery,Ohio State University Wexner Medical Center, 4Department of Medicine,Ohio State University Wexner Medical Center
Chapters
- 00:04Title
- 00:36Preparation of the Portal Vein Cuff and Bile Duct Cannula
- 01:20Liver Procurement Procedure
- 05:24Ex Vivo Normothermic Liver Perfusion
- 06:58Results: Analysis of Tissue Damage in Base Perfusate-only and Base Perfusate and Plus PEG-CAT Groups
- 07:56Conclusion
C'è una carenza significativa donatore di fegato, e i criteri per i donatori di fegato sono stati ampliati. Perfusione normotermica ex vivo del fegato (NEVLP) è stato sviluppato per valutare e modificare la funzione dell'organo. Questo studio dimostra un modello del ratto di NEVLP e verifica la capacità di pegylated-catalasi, per attenuare la lesione di conservazione del fegato.
