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JoVE Journal
Immunology and Infection

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Antigenic Liposomes for Generation of Disease-specific Antibodies
 

Antigenic Liposomes for Generation of Disease-specific Antibodies

Article DOI: 10.3791/58285
October 25th, 2018

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Summary October 25th, 2018

Described is the preparation of antigenic liposomal nanoparticles and their use in stimulating B-cell activation in vitro and in vivo. Consistent and robust antibody responses led to the development of a new peanut allergy model. The protocol for generating antigenic liposomes can be extended to different antigens and immunization models.

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