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基因治疗诱导聚化涂层保护 dna 折纸纳米结构
JoVE Journal
Chemistry
This content is Free Access.
JoVE Journal Chemistry
Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
DOI:

08:30 min

January 19, 2019

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Chapters

  • 00:04Title
  • 01:12Polyplex Formation
  • 02:16Agarose Gel Electrophoresis
  • 03:12Stability of Polyplexes Towards DNase I
  • 04:36Testing the Addressability of Horseradish Peroxidase Enzyme (HRP)-functionalized DNA Origami (HRP-NR) Upon Polycation Coating
  • 05:44Results: Characterization of DNA Origami Polyplexes
  • 07:42Conclusion

Summary

Automatic Translation

本文介绍了一种利用天然阳离子多糖壳聚糖和合成线性聚乙烯胺 (lpei) 涂层保护镁-贫化和富含核酸酶介质中 dna 折纸纳米结构的方案。

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