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癌地致小鼠膀胱肿瘤的磁共振成像评价

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Cancer Research

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JoVE Journal Cancer Research

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

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癌地致小鼠膀胱肿瘤的磁共振成像评价

DOI:

10.3791/59101-v

•

05:19 min

•

March 29, 2019

•

Alexander P. Glaser, Daniele Procissi, Yanni Yu, Joshua J. Meeks

¹Department of Surgery, Division of Urology,NorthShore University HealthSystem, ²Department of Radiology,Northwestern University Feinberg School of Medicine, ³Department of Urology,Northwestern University Feinberg School of Medicine

Chapters

00:04Title
00:29N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) Tumor Induction and Magnetic Resonance Imaging (MRI) Acquisition and Analysis
02:56Bladder Dissection
03:56Results: Representative MRI Assessment of BBN-Induced Murine Bladder Tumors
04:43Conclusion

Summary

Automatic Translation

小鼠膀胱肿瘤是由 n-丁基-n-(4-羟基丁基) 亚硝胺致癌物 (BBN) 诱导的。膀胱肿瘤的产生是异质性的;因此, 在随机化进行实验治疗之前, 需要对肿瘤负担进行准确的评估。在这里, 我们提出了一个快速, 可靠的 MRI 方案, 以评估肿瘤的大小和阶段。

Tags

Magnetic Resonance Imaging Carcinogen-induced Murine Bladder Tumors BBN C57 Black Six Mice Subcutaneous Injection Rectal Temperature Probe Quadrature Receiver Coil True Fast Imaging With Steady-state Progression Axial Coronal Sagittal Planes Image Analysis Software

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