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分散(Ex Vivo)的毛骨球模型,去除了除位肌肉,用于在膀胱填充期间直接进入苏布罗氦
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Medicine
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JoVE Journal
Medicine
A Decentralized (Ex Vivo) Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling
Please note that all translations are automatically generated.
Click here for the English version.
分散(Ex Vivo)的毛骨球模型,去除了除位肌肉,用于在膀胱填充期间直接进入苏布罗氦
DOI:
10.3791/60344-v
•
06:36 min
•
November 28, 2019
•
Leonie Durnin
2
,
Robert D. Corrigan
,
Kenton M. Sanders
,
Violeta N. Mutafova-Yambolieva
1
Department of Physiology and Cell Biology
,
University of Nevada Reno School of Medicine
,
2
Charles River Laboratories Inc.
Chapters
00:05
Title
00:40
Detrusor-Free Bladder Preparation Dissection
02:41
Denuded Bladder Preparation Filling and Mediator Detection
03:40
Results: Representative Denuded Murine Bladder Preparation Assessment
05:44
Conclusion
Summary
Automatic Translation
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Automatic Translation
无分泌物的膀胱模型允许直接进入亚尿层,以研究在尿液储存和排空期间调节亚尿层/拉米纳尿体中生物活性介质可用性的本地机制。制备与填充完整膀胱非常相似,允许在无系统影响的情况下进行压力体积研究。
Tags
Decentralized Bladder Model
Detrusor Muscle Removal
Suburothelium
Bladder Filling
Urothelial Mediators
Signaling Mechanisms
Bladder Excitability
Murine Bladder Specimen
Dissection
Oxygenated KBS
Detrusor Muscle Layer
Bladder Mucosa
Catheter Insertion
Organ Dish
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