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1Department of Surgery, Division of Vascular Surgery,University of North Carolina at Chapel Hill, 2Center for Nanotechnology in Drug Delivery,University of North Carolina at Chapel Hill, 3Curriculum in Toxicology & Environmental Medicine,University of North Carolina at Chapel Hill, 4Department of Cell Biology & Physiology,University of North Carolina at Chapel Hill, 5McAllister Heart Institute,University of North Carolina at Chapel Hill
Chapters
- 00:05Introduction
- 00:47Common Carotid Artery (CCA) Identification
- 02:16CCA Dissection
- 03:29Carotid Artery Pressure-Controlled Segmental Balloon Injury
- 05:36Results: Representative Hematoxylin & Eosin (H&E) and Light Sheet Fluorescence Microscopy Imaging
- 06:19Conclusion
Die Ratten-Carotis-Arterie Ballon-Verletzung imitiert das klinische Angioplastie-Verfahren zur Wiederherstellung des Blutflusses in atherosklerotischen Gefäßen. Dieses Modell induziert die arterielle Verletzungsreaktion, indem es die arterielle Wand distend und die Intimschicht von Endothelzellen denudiert, was letztlich zu einer Umgestaltung und einer intimalen hyperplastischen Reaktion führt.
