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1Department of Surgery, Division of Vascular Surgery,University of North Carolina at Chapel Hill, 2Center for Nanotechnology in Drug Delivery,University of North Carolina at Chapel Hill, 3Curriculum in Toxicology & Environmental Medicine,University of North Carolina at Chapel Hill, 4Department of Cell Biology & Physiology,University of North Carolina at Chapel Hill, 5McAllister Heart Institute,University of North Carolina at Chapel Hill
Chapters
- 00:05Introduction
- 00:47Common Carotid Artery (CCA) Identification
- 02:16CCA Dissection
- 03:29Carotid Artery Pressure-Controlled Segmental Balloon Injury
- 05:36Results: Representative Hematoxylin & Eosin (H&E) and Light Sheet Fluorescence Microscopy Imaging
- 06:19Conclusion
La lesione del palloncino dell'arteria carotide del ratto imita la procedura di angioplastica clinica eseguita per ripristinare il flusso sanguigno nei vasi aterosclerotici. Questo modello induce la risposta alle lesioni arteriose tendendo la parete arteriosa e denudendo lo strato intimale delle cellule endoteliali, causando infine rimodellamento e una risposta iperplastica intimale.
