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Neuroscience

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JoVE Journal Neuroscience
Preparação de fatias hipocampais humanas agudas para gravações eletrofisiológicas
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Preparação de fatias hipocampais humanas agudas para gravações eletrofisiológicas

Article DOI: 10.3791/61085-v • 07:31 min • May 7th, 2020
May 7th, 2020 •
1, 1,2, 3, 3, 3, 1, 1,2
1Department of Neurology with Experimental Neurology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 2NeuroCure Cluster of Excellence, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 3Department of Neurosurgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health

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O protocolo apresentado descreve o transporte e a preparação de tecido hipocampal humano ressecado com o objetivo final de usar fatias cerebrais vitais como uma ferramenta de avaliação pré-clínico para potenciais substâncias antiepilépticas.

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Neurociência Edição 159 eletrofisiologia epilepsia desenvolvimento de drogas humano hipocampo ex vivo
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