3D Cell-Printed Hypoxic Cancer-on-a-Chip for Recapitulating Pathologic Progression of Solid Cancer

Wonbin Park; Mihyeon Bae; Minseon Hwang; Jinah Jang; Dong-Woo Cho; Hee-Gyeong Yi

doi:10.3791/61945

Journal

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Bioengineering

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Cancer hypoxique sur puce imprimé par cellules 3D pour récapituler la progression pathologique du cancer solide

3D Cell-Printed Hypoxic Cancer-on-a-Chip for Recapitulating Pathologic Progression of Solid Cancer

JoVE Journal
Bioengineering

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JoVE Journal Bioengineering

3D Cell-Printed Hypoxic Cancer-on-a-Chip for Recapitulating Pathologic Progression of Solid Cancer

Cancer hypoxique sur puce imprimé par cellules 3D pour récapituler la progression pathologique du cancer solide

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4,652 Views

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10:51 min

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January 05, 2021

DOI:

10.3791/61945-v

DOI:

10.3791/61945-v

•

10:51 min

January 05, 2021

•

4633 Views

Wonbin Park*¹, Mihyeon Bae*¹, Minseon Hwang¹, Jinah Jang², Dong-Woo Cho¹, Hee-Gyeong Yi^1,3

¹Department of Mechanical Engineering,Pohang University of Science and Technology (POSTECH)²Department of Creative IT Engineering,Pohang University of Science and Technology (POSTECH)³Department of Rural and Biosystems Engineering, College of Agriculture and Life Sciences,Chonnam National University

Summary

L’hypoxie est une caractéristique du microenvironnement tumoral et joue un rôle crucial dans la progression du cancer. Cet article décrit le processus de fabrication d’un cancer-sur-une-puce hypoxique basé sur la technologie 3D d’impression cellulaire pour récapituler une pathologie hypoxie-connexe du cancer.