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3D Cell-Printed Hypoxic Cancer-on-a-Chip Para Recapitular la Progresión Patológica Del Cáncer Sólido
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1Department of Mechanical Engineering,Pohang University of Science and Technology (POSTECH), 2Department of Creative IT Engineering,Pohang University of Science and Technology (POSTECH), 3Department of Rural and Biosystems Engineering, College of Agriculture and Life Sciences,Chonnam National University
Chapters
- 00:05Introduction
- 00:56Collagen Pre-Gel Solution Preparation
- 01:471% Neutralized Collagen Pre-Gel Solution pH Adjustment
- 03:12Gas-Permeable Barrier 3D Printing
- 04:20Polydimethylsiloxane (PDMS) Barrier Casting
- 05:291% Neutralized Collagen Pre-Gel Solution Cell Mixing
- 06:19Cancer-Stroma Concentric Ring 3D Cell Printing
- 07:39Hypoxic Cancer-on-a-Chip Maintenance
- 08:11Results: Representative Solid Pathologic Cancer Progression on a 3D Cell-Printed Hypoxic Cancer-on-a-Chip
- 10:06Conclusion
La hipoxia es un sello distintivo del microambiente tumoral y desempeña un papel crucial en la progresión del cáncer. Este artículo describe el proceso de la fabricación de un cáncer-en-una-viruta hipóxico basado en tecnología de célula-impresión 3D para recapitular una patología hipoxia-relacionada del cáncer.
