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Journal / Bioengineering / Microfluïdisch model om de eerste gebeurtenis van …
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JoVE Journal Bioengineering
Microfluïdisch model om de eerste gebeurtenis van neovascularisatie na te bootsen
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Microfluïdisch model om de eerste gebeurtenis van neovascularisatie na te bootsen

Article DOI: 10.3791/62003-v • 10:01 min • April 10th, 2021
April 10th, 2021 •
1, 1, 1, 4, 1, 1, 1, 3, 1,2
1Beijing Advanced Innovation Centre for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Chinese Education Ministry, School of Biological Science and Medical Engineering, Beihang University, 2School of Engineering Medicine, Beihang University, 3Artificial Intelligence Key Laboratory of Sichuan Province, School of Automation and Information Engineering, Sichuan University of Science and Engineering, 4Beijing Research Center of Urban System Engineering

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Hier bieden we een microfluïdische chip en een automatisch gecontroleerd, zeer efficiënt circulatiemicrofluïdisch systeem dat de initiële micromilieu van neovascularisatie samenvat, waardoor endotheelcellen (EC's) tegelijkertijd kunnen worden gestimuleerd door hoge luminale schuifspanning, fysiologisch niveau van transendotheliale stroom en verschillende vasculaire endotheliale groeifactor (VEGF) distributie tegelijkertijd.

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Bio-engineering neovascularisatie microfluïdica schuifspanning micromilieu transendotheelstroom 3D-cultuur
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