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Journal / Bioengineering / Mikrofluidisches Modell zur Nachahmung des ersten …
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JoVE Journal Bioengineering
Mikrofluidisches Modell zur Nachahmung des ersten Ereignisses der Neovaskularisation
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Mikrofluidisches Modell zur Nachahmung des ersten Ereignisses der Neovaskularisation

Article DOI: 10.3791/62003-v • 10:01 min • April 10th, 2021
April 10th, 2021 •
1, 1, 1, 4, 1, 1, 1, 3, 1,2
1Beijing Advanced Innovation Centre for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Chinese Education Ministry, School of Biological Science and Medical Engineering, Beihang University, 2School of Engineering Medicine, Beihang University, 3Artificial Intelligence Key Laboratory of Sichuan Province, School of Automation and Information Engineering, Sichuan University of Science and Engineering, 4Beijing Research Center of Urban System Engineering

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Hier bieten wir einen mikrofluidischen Chip und ein automatisch gesteuertes, hocheffizientes Kreislauf-Mikrofluidsystem, das die anfängliche Mikroumgebung der Neovaskularisation rekapituliert und es ermöglicht, Endothelzellen (ECs) durch hohe Luminalscherspannung, physiologischen Transendothelfluss und verschiedene vaskuläre endotheliale Wachstumsfaktor (VEGF) gleichzeitig zu stimulieren.

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Bioengineering Ausgabe 170 Neovaskularisation Mikrofluidik Scherstress Mikroumgebung transendotheliale Strömung 3D-Kultur
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