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Uso de un modelo murino de estrés psicosocial en el embarazo como paradigma traslacionalmente relevante para los trastornos psiquiátricos en madres y bebés
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Uso de un modelo murino de estrés psicosocial en el embarazo como paradigma traslacionalmente relevante para los trastornos psiquiátricos en madres y bebés

Article DOI: 10.3791/62464-v • 06:39 min • June 13th, 2021
June 13th, 2021 •
1,2,3, 4, 1,2,3
1Molecular Developmental Biology Program, Cincinnati Children’s Hospital Medical Center, 2Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, 3Department of Pediatrics, University of Cincinnati College of Medicine, 4Division of Veterinary Services, Cincinnati Children’s Hospital Medical Center

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El paradigma del estrés psicosocial crónico (CGS) emplea factores estresantes clínicamente relevantes durante el embarazo en ratones para modelar trastornos psiquiátricos de madres y bebés. Aquí, proporcionamos un procedimiento paso a paso para aplicar el paradigma CGS y las evaluaciones posteriores para validar este modelo.

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Comportamiento Número 172 estrés psicosocial crónico embarazo comportamiento función neuroendocrina estado de ánimo perinatal y trastornos de ansiedad
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