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JoVE Journal
Immunology and Infection

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使用类似人类单细胞的THP-1白血病细胞系,将巨噬细胞分化和极化成M2样表型
 
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使用类似人类单细胞的THP-1白血病细胞系,将巨噬细胞分化和极化成M2样表型

Article DOI: 10.3791/62652-v
August 2nd, 2021

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Summary August 2nd, 2021

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M2样肿瘤相关巨噬细胞(TAM)与肿瘤进展和癌症预后不佳有关。本协议作为在 14 天内可重复区分和分化 THP-1 单细胞状细胞成 M2 样巨噬细胞的详细指南。该模型是研究TAM在肿瘤微环境内的抗炎作用的基础。

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